Angular Substituted Polycyclic Compounds. II. Reaction of Cholest-4-en-3-one with Metallic Cyano Complexes.

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概要

• 論文の詳細を見る

• Cyanation of cholest-4-en-3-one (I) was attempted with CN-Mg-I, Li[Al(CN)_4], H[Al(tert-BuO)_3CN], and H[Al(iso-PrO)_8CN] respectively to give the cyano ketone compounds, but in the case of H[Al(iso-PrO)_3CN], 1,3-cyanohydrins were obtained. The reduction of epimeric 3-oxo-cholestane-5-carbonitrile with aluminum isopropoxide and with sodium borohydride afforded the four cyanohydrins which were designated as the formulae (VIII), (VII), (XII), and (XIII).

• 公益社団法人日本薬学会の論文
• 1961-11-25

著者

• 平井 章一

  Shionogi Research Laboratories Shionogi & Co. Ltd.

• 平井 章一

  Shionogi Research Laboratory Shionogi & Co. Ltd.

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• Angular Substituted Polycyclic Compounds. II. Reaction of Cholest-4-en-3-one with Metallic Cyano Complexes.
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