Studies on Streptomyces Antibiotic, Cycloheximide. VI. The Absolute Configuration of Naramycin-A (Cycloheximide) and its Isomeric Naramycin-B.
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概要
- 論文の詳細を見る
The stereochemical considerations of dihydrogenated cycloheximide and its acylates were made and it was found that α-hydroxyl group in cycloheximide is situated quite closely to equatorial 1-hydroxyl group which is obtainable by reducing the carbonyl group in the molecule. This finding, together with previously reported information, leads to the conclusion that Naramycin-A should have (4S : 6S : αS)-configuration, and its isomeric Naramycin-B should have (4S : 6R : αS)-configuration.
- 公益社団法人日本薬学会の論文
- 1959-09-20
著者
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奥田 朝晴
Microbial Chemistry Research Laboratory, Tanabe Seiyaku Co., Ltd.
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奥田 朝晴
Tokyo Research Laboratory Tanabe Seiyaku Co. Ltd.
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奥田 朝晴
Microbial Chemistry Research Laboratory Tanabe Seiyaku Co. Ltd.
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