Studies on Nucleic Acid Antagonists. III. Growth Inhibitory Effect of 5-Phenylazopyrimidine Derivatives on Streptococcus faecalis.

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概要

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• Results of growth inhibition tests and of the reversal experiments on the growth of Str. faecalis by 5-phenylazopyrimidine derivatives were described. The 5-phenylazopyrimidine derivatives were classified into following two groups on the basis of their antagonistic pattern. The first group consists of those compounds whose growth inhibitory activity is reversed by thymine or leucovorin but not by folic acid, and the second group, those compounds whose inhibitory activity is reversed by thymine or leucovorin, as well as by folic acid.

• 公益社団法人日本薬学会の論文
• 1959-02-10

著者

• 川島 實

  Research Laboratories Takeda Pharmaceutical Industries Ltd.

関連論文

• Studies on Nucleic Acid Antagonists. IV. Inhibitory Effect of 5-Phenylazopyrimidines on the Enzymatic Conversion of Folic Acid to Citrovorum Factor in vitro.
• Studies on Nucleic Acid Antagonists. III. Growth Inhibitory Effect of 5-Phenylazopyrimidine Derivatives on Streptococcus faecalis.

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