Synthesis and in Vitro Antiprotozoal Activity of Thiophene Ring-Containing Quinones

スポンサーリンク

概要

• 論文の詳細を見る

• A series of quinones (3a-i, 4-9,11) and aromatic compounds (2a, 2b, 2g) containing the thiophene ring were tested in vitro against the trypomastigote form of Trypanosoma cruzi and the promastigote forms of Leishmania. The quinones 3a-i, 4,5a, b, 6 and 9 having the thiophene ring fused to a quinone nucleus were the most active members of the series. The electron affinities of the benzo[b]thiophene-4,7-quinones 3,evaluated by their LUMO energies and halfwave potentials, are reported.

• 公益社団法人日本薬学会の論文
• 1999-09-15

著者

• Rojas De

  Iics (institute De Investigaciones En Ciencias De La Salud)

• Inchausti Alba

  Iics (institute De Investigaciones En Ciencias De La Salud)

• Valderrama Claudio

  Facultad De Quimica Pontificia Universidad Catolica De Chile

• Valderrama Jaime

  Facultad De Quimica Pontificia Universidad Catolica De Chile

• FOURNET Alain

  Institute de Recherche pour le Developpement (ex-ORSTOM)

• BASTIAS Sandra

  Facultad de Quimica, Pontificia Universidad Catolica de Chile

• ASTUDILLO Claudio

  Facultad de Quimica, Pontificia Universidad Catolica de Chile

• YALUFF Gloria

  IICS (Institute de Investigaciones en Ciencias de la Salud)

• Bastias Sandra

  Facultad De Quimica Pontificia Universidad Catolica De Chile

• Astudillo Claudio

  Facultad De Quimica Pontificia Universidad Catolica De Chile

• FOURNET Alain

  Institut de Recherche pour le Developpement (IRD)

関連論文

• Synthesis and in Vitro Antiprotozoal Activity of Thiophene Ring-Containing Quinones
• Studies on Quinones. Part 37. Synthesis and Biological Activity of o-Aminoester Functionalised Benzo- and Naphtho [2,3-b]-thiophenequinones

スポンサーリンク