Indirect Titrimetric and Spectrophotometric Methods for the Determination of Some Phenothiazine Psychotropics

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概要

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• A titrimetric and a spectrophotometric method herein described for the determination of phenothiazine psychotropics. In the titrimetric method, phenothiazines are reacted with a known excess of potassium dichromate under acidic conditions and after the completion of the reaction, unreacted dichromate is backtitrated with ammonium ferrous sulphate. In the spectrophotometric method, the unreacted dichromate is reacted with s-diphenylcarbazide under acidic conditions and the absorbance measured at 540 nm. The proposed methods were successfully applied to the determination of phenothiazines in pharmaceutical preparations. The reliability of the assays was established by parallel determination by the official methods of British pharmacopoeia.

• 公益社団法人日本薬学会の論文
• 1999-10-15

著者

• Manjunatha Swamy

  Department Of Studies In Chemistry University Of Mysore

• Basavaiah K

  Univ. Mysore Mysore Ind

• Basavaiah Kanakapura

  Department Of Chemistry University Of Mysore

• Manjunatha Swamy

  Department Of Chemistry University Of Mysore

• KRISHNAMURTHY Gopalaiah

  Department of Chemistry, PES College of Science

• Krishnamurthy Gopalaiah

  Department Of Chemistry Pes College Of Science

関連論文

• A Highly Sensitive Spectrophotometric Method for the Determination of Some Phenothiazine Antipsychotics Using Chloramine-T and Indigocarmine
• Indirect Titrimetric and Spectrophotometric Methods for the Determination of Some Phenothiazine Psychotropics
• Use of an Oxidation Reaction for the Quantitative Determination of Albendazole with Chloramine - T and Acid Dyes

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