3, 7-Dimethylguanine, a New Purine from a Philippine Sponge Zyzzya fuliginosa

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概要

• 論文の詳細を見る

• A new purine 3, 7-dimenthylguanine(1)has been isolated from the marine sponge Zyzzya fuliginosa, along with the known metabolites, makaluvamines A, C, K(2-4), 4-hydroxyphenylacetic acid(5), methyl ester of 4-hydroxyphenylacetic acid(6), 4-hydroxyphenethyl alcohol(7), L-phenylalanine(8)and L-tryptophan(9). The structure of 3, 7-dimethylguanine(1)was elucidated by analysis of 1D and 2D(one- and two-dimensional)NMR[HMQC(heteronuclear multiple quantum coherence), gHMBC(heteronuclear multiple bond connecivity), ^1H-^<15>N gHMBC]data, mass spectroscopy data, and by comparison with 3, 7-dimethylisoguanine(10).

• 公益社団法人日本薬学会の論文
• 2001-12-01

著者

• Concepcion Gisela

  Marine Science Institute University Of The Philippines

• MANGALINDAN Gina

  Marine Science Institute, University of the Philippines

• IRELAND Chris

  Department of Medicinal Chemistry, University of Utah

• TASDEMIR Deniz

  Department of Medicinal Chemistry, University of Utah

• HARPER Mary

  Department of Medicinal Chemistry, University of Utah

• Ireland Chris

  Department Of Medicinal Chemistry University Of Utah

• Mangalindan Gina

  Marine Science Institute University Of The Philippines

• Harper Mary

  Department Of Medicinal Chemistry University Of Utah

• Tasdemir Deniz

  Department Of Pharmacognosy Faculty Of Pharmacy Hacettepe University

関連論文

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• Platelet Aggregation Inhibitors from Philippine Marine Invertebrate Samples Screened in a New Microplate Assay
• 3, 7-Dimethylguanine, a New Purine from a Philippine Sponge Zyzzya fuliginosa
• Lucidin Type Anthraquinone Glycosides from Putoria calabrica
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• Phenylethanoid Glycosides from Digitalis ferruginea subsp. ferruginea (=D. aurea LINDLEY) (Scrophulariacear)
• New Destruxins from the Marine-derived Fungus Beauveria felina
• ILI-1 Chemistry and Mechanism of Action of Marine Natural Product Antitumor Agents(Isolation and Structure Elucidation of Natural Products)

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