Indirect Potentiometric Titration of Ascorbic Acid in Pharmaceutical Preparations Using Copper Based Mercury Film Electrode
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概要
- 論文の詳細を見る
A simple and rapid potentiometric method for the estimation of ascorbic acid in pharmaceutical dosage forms has been developed. The method is based on treating ascorbic acid with iodine and titration of the iodide produced equivalent to ascorbic acid with silver nitrate using Copper Based Mercury Film Electrode (CBMFE) as an indicator electrode. Interference study was carried to check possible interference of usual excipients and other vitamins. The precision and accuracy of the method was assessed by the application of lack-of-fit test and other statistical methods. The results of the proposed method and British Pharmacopoeia method were compared using F and t-statistical tests of significance.
- 社団法人日本薬学会の論文
- 2004-01-01
著者
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Abdul Kamal
Department Of Chemistry The New College
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Hameed Abdul
Department Of Chemistry The New College
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RIYAZUDDIN Patel
Department of Analytical Chemistry, University of Madras
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Riyazuddin Patel
Department Of Analytical Chemistry University Of Madras
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Riyazuddin P
Department Of Analytical Chemistry University Of Madras
関連論文
- Indirect Potentiometric Titration of Ascorbic Acid in Pharmaceutical Preparations Using Copper Based Mercury Film Electrode
- Indirect Potentiometric Titration of Sulphamethoxazole in the Presence of Trimethoprim in Co-trimazole Tablets Using Copper Based Mercury Film Electrode