Synthesis, Characterization, and Antibacterial Activities of Some Rare Earth Metal Complexes of Pipemidic Acid

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概要

• 論文の詳細を見る

• Eight new solid complexes of pipemidic acid (PPA) with trichlorizated rare earth metals LaCl_3, CeCl_3, PrCl_3, NdCl_3, SmCl_3, TbCl_3, DyCl_3, and YCl_3 have been synthesized. The complexes were characterized by elemental analyses, IR, NMR, and molar conductance measurements. The general formulas of the complexes are [M(PPA)_4]Cl_3, (M=Ce(III), Pr(III), Nd(III), Sm(III), Tb(III), Dy(III), Y(III)), and [La(PPA)_4Cl]Cl_2. At the same time, the antibacterial activities of PPA and four of its complexes were tested. The results show that PPA and its complexes all have inhibitory action against bacteria of Escherichia coli, Bacillus subtilis, Streptococcus pneumoniae, and Pseudomonas aeruginosa but not Staphylococcus aureus. We compared their antibacterial activities and found that the antibacterial activity of [La(PPA)_4Cl]Cl_2 against S. pneumoniae is much stronger than that of PPA and the other complexes.

• 公益社団法人日本薬学会の論文
• 2003-05-01

著者

• Yang L

  College Of Chemistry And Environmental Science Henan Normal University

• YANG Lin

  College of Chemistry and Environmental Science, Henan Normal University

• TAO Dongliang

  College of Chemistry and Environmental Science, Henan Normal University

• YANG Xiaoli

  College of Chemistry and Environmental Science, Henan Normal University

• LI Yongfang

  College of Chemistry and Environmental Science, Henan Normal University

• Yang Xiaoli

  College Of Chemistry And Environmental Science Henan Normal University

• Tao Dongliang

  College Of Chemistry And Environmental Science Henan Normal University

• Yang Lin

  College Of Chemistry And Environmental Science Henan Normal University

関連論文

• Synthesis, Characterization, and Antibacterial Activities of Some Rare Earth Metal Complexes of Pipemidic Acid
• Study of amino acids as nitrogen source in Chlamydomonas reinhardtii

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