Tetracyclic Triterpenoids from the Leaves of Azadirachta indica and Their Insecticidal Activities

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概要

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• A new tetranortriterpenoid, meliatetraolenone [24,25,26,27-tetranor-apotirucalla-(apoeupha}-6α-O-methyl,7α-senecioyl(7-dcacetyl)-11α,12α,21,23-tetrahydroxy-21,23-epoxy-2,14,20(22)-trien-1,16-dione] (1) was isolated from the methanolic extract of fresh leaves of Azadirachta indica along with the known compound odoratone (3) which was hitherto unreported from this source. Their structures have been elucidated by spectral studies including 2D NMR. The insecticidal activities of 1 as well as those of odoratone (3) are reported. 1 and odoratone both shewed mortality on fourth instar larvae of mosquitoes (Anopheles Stephensi) with LC_50 values of 16 and 154 ppm, respectively.

• 公益社団法人日本薬学会の論文
• 2003-04-01

著者

• Siddiqui B

  Univ. Karachi Karachi Pak

• Siddiqui Bina

  H. E. J. Research Institute Of Chemistry International Centre For Chemical Sciences University Of Ka

• Naqvi Syed

  Department Of Urology Sindh Institute Of Urology And Transplantation

• Naqvi Syed

  Department Of Pharmacology Baqai Medical University

• GULZAR Tahsin

  H. E. J. Research Institute of Chemistry, International Centre for Chemical Sciences, University of

• AFSHAN Farhana

  H. E. J. Research Institute of Chemistry, International Centre for Chemical Sciences, University of

• SULTANA Razia

  H. E. J. Research Institute of Chemistry, University of Karachi

• TARIQ Rajput

  Department of Zoology, University of Karachi

• Sultana Razia

  H. E. J. Research Institute Of Chemistry University Of Karachi

• Tariq Rajput

  Department Of Zoology University Of Karachi

• Gulzar T

  H. E. J. Research Institute Of Chemistry International Centre For Chemical Sciences University Of Ka

• Afshan Farhana

  H. E. J. Research Institute Of Chemistry International Centre For Chemical Sciences University Of Ka

• Naqvi Syed

  Department Of Biochemistry Faculty Of Biological Sciences Quaid-i-azam University

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