O-Demethylation and Sulfation of 7-Methoxylated Flavanones by Cunninghamella elegans
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概要
- 論文の詳細を見る
Metabolism of 7-O-methylnaringenin (sakuranetin) by Cunninghamella elegans NRRL 1392 yielded naringenin and naringenin-4'-sulfate. C. elegans also converted 5,3',4'-trihydroxy-7-methoxyflavanone into eriodictyol-4'-sulfate. Furthermore, incubation of 5,4'-dihydroxy-7,3'-dimethoxyflavanone with the same fungus gave homoeriodictyol (5,7,4'-trihydroxy-3'-methoxyflavanone) and homoeriodicytol-7-sulfate. The structures of the new metabolites were established by spectral analysis including 2D-NMR, HR-ESI-FT-MS beside hydrolysis by acid.
- 公益社団法人日本薬学会の論文
- 2003-02-01
著者
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Ibrahim Abdel-rahim
Pharmacognosy Departments College Of Pharmacy Tanta University
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Galal Ahmed
College Of Pharmacy Cairo University
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Ahmed Mohammed
College Of Pharmacy King Saud University
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MOSSA Gabir
College of Pharmacy, King Saud University
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Mossa Gabir
College Of Pharmacy King Saud University