An Efficient Procedure for the Preparation of (1S, 3R)- and (1S, 3S)-1-Amino-3-(hydroxymethyl) cyclopentanes

スポンサーリンク

概要

• 論文の詳細を見る

• Enantiomerically pure (1S, 3S) - and (1S, 3R) -l-amino-3- (hydroxymethyl) cyclopentanes have been efficiently synthesized from L-aspartic acid. The title compounds are isosteres of ribose and may be used to construct nucleoside analogs with important antiviral and antineoplastic activities as demonstrated by a concise total synthesis of (+) -4'-deoxycarbapentostatin nucleoside.

• 社団法人日本薬学会の論文
• 2003-10-01

著者

• Chen Yuewu

  Department Of Chemistry University Of California

• Ahn Jin

  Department Of Computer Science Kyonggi University

• RAPOPORT Henry

  Department of Chemistry, University of California

• MOHAREB Rafat

  Department of Chemistry, Faculty of Science, Cairo University

• SIM Tae

  Genomics Institute of the Novartis Resarch

• HO Jonathan

  Merck & Co., Inc.

• Sim T

  Genomics Institute Of The Novartis Resarch

• Ho Jonathan

  Merck & Co. Inc.

• Ahn Jin

  Department Of Chemistry Medicinal Science Division Korea Research Institute Of Chemical Technology

• Mohareb Rafat

  Department Of Chemistry Faculty Of Science Cairo University

• Rapoport Henry

  Department Of Chemistry University Of California

関連論文

• An Efficient Procedure for the Preparation of (1S, 3R)- and (1S, 3S)-1-Amino-3-(hydroxymethyl) cyclopentanes
• Application-Level Causally Ordered Broadcast for Large-Scale Group Communication(Dependable Computing)

スポンサーリンク