水溶液中における多点相互作用に基づく新機能性超分子の創製
スポンサーリンク
概要
- 論文の詳細を見る
Novel supramolecular chemistry of multinuclear zinc (II) complexes in aqueous solution has been created by utilizing multiple interactions with polyanions. We have established reliable and convenient synthetic methods of multidentate macrocyclic polyamines and their zinc (II) complexes and thereby undertook a focused investigation of four topics: 1) efficient inhibition of photo [2 + 2] cycloaddition of thymidine dimer by dimeric zinc (II) complexes; 2) selective extraction and transport of thymidine nucleotide derivatives from the aqueous phase to the organic phase by lipophilic zinc (II) complexes and selective recognition of thymidine nucleotides by ditopic zinc (II) complexes in aqueous solution; 3) supramolecular polyhedrons formed by self-assembly of a trimeric zinc (II) complex with cyanuric acid or trithiocyanuric acid; and 4) a selective fluorescent probe for lanthanide ions such as Y^3+ and La^3+ based on a double-functionalized ligand with carbamoyl and dansyl groups. This knowledge should afford new methodology for supramolecular chemistry in aqueous solution.
- 社団法人日本薬学会の論文
- 2002-10-01