Antimicrobial Activity of Some Pentacyclic Triterpenes and Their Synthesized 3-O-Lipophilic Chains(Medicinal Chemistry)

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概要

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• The major metabolites of Diopsyros melanoxylon viz. amyrins and ursolic acid and their lipophilic 3-0-fatty acid ester chains (C_<12>-C_<18>), which are synthesized now under mild esterification conditions in excellent yields (80-95%), were evaluated for their antimicrobial activity against a series of Gram positive and Gram negative bacteria. Significantly these compounds were found to exhibit potent activity against Gram negative bacteria Pseudomonas syringae (ATCC #13457) and fairly good activity against Gram positive bacteria, Bacillus sphaericus (ATCC #14577) and Bacillus subtilis (ATCC #6051).

• 公益社団法人日本薬学会の論文
• 2004-10-01

著者

• Mahapatra Anita

  Centre For Herbal Drugs Department Regional Research Laboratory (csir)

• MALLAVADHANI Uppuluri

  Centre for Herbal Drugs Department, Regional Research Laboratory (CSIR)

• JAMIL Kaiser

  Biology & Biotechnology Department, Indian Institute of Chemical Technology (CSIR)

• REDDY Peddi

  Biology & Biotechnology Department, Indian Institute of Chemical Technology (CSIR)

• Jamil Kaiser

  Biology & Biotechnology Department Indian Institute Of Chemical Technology (csir)

• Mallavadhani Uppuluri

  Traditional And Herbal Drugs Dep. Regional Res. Lab. Ind

• Reddy Peddi

  Biology & Biotechnology Department Indian Institute Of Chemical Technology (csir)

関連論文

• Antimicrobial Activity of Some Pentacyclic Triterpenes and Their Synthesized 3-O-Lipophilic Chains(Medicinal Chemistry)
• Three New Pentacyclic Triterpenes and Some Flavonoids from the Fruits of an Indian Ayurvedic Plant Dendrophthoe falcata and Their Estrogen Receptor Binding Activity

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