CT 9800 Xenon CBF Imaging System を用いた局所脳血流量の評価 : 理論的解析法との比較

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In order to evaluate the accuracy of the regional cerebral blood flow (r-CBF) measured by CT 9800 Xenon CBF Imaging System which was provided by G.E, a theoretical quantitative analysis of r-CBF and CT 9800 Xenon CBF Imaging System were preformed in 20 cases, and these obtained values were compared with each method. The theoretical quantitative analysis of r-CBF was done as follows; Time activity curves of xenon gas concentration were generated from region of interest (ROI) over the gray matter and white matter. An exponential function was fitted to the time activity curves to determine build up rate (K_a) and blood-brain partition coefficent (λ_a). K_a and λ_a were 0.83±0.53 (mean±SD), 0.86±0.28 in the gray matter, and 0.39±0.29, 0.79±0.53 in the white matter respectively. A correlation coefficient of 0.53, a slope of 0.79, and a zero intercept of 10.69 were obtained to compared with both methods. It is important for clinical estimations of r-CBF to understand the fundamental parameter which build in the CT.
公益社団法人日本放射線技術学会の論文
1992-09-01