脳Perfusion CTにおける造影剤注入条件の検討

概要

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Perfusion computed tomography (CT) has great value for detecting stroke and evaluating blood flow in the brain. With perfusion CT, it is possible to obtain two absolute values, cerebral blood flow (CBF) (ml/min/100g) and cerebral blood volume (CBV) (%). In using this examination, the main problem is the method of iodine injection. The maximum slope of time-attenuation curve in organs must be reached before the peak enhancement time of the sagittal sinus. To solve this problem, we used a new method in which total injection volume is 30ml, and the rate of injection is 9ml/sec. The data acquisition time is one second for each scan, and the time interval is one second, for 20 scans in total. With this method, we can obtain reliable information on blood flow in the damaged brain. The most common examination used for the detection of brain blood flow is single-phased dynamic CT with Xe inhalation. However, the Xe inhalant examination is difficult to use in the routine clinical setting. Perfusion CT will be more useful for the detection of brain blood flow.
社団法人日本放射線技術学会の論文
2002-07-20