心電図同期心筋SPECTの定量的解析法(QGS-advanced)における^<201>Tlの有用性について : 心臓超音波検査法との比較検討

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The aim of this study was to assess the clinical significance and validity of the advanced quantitative 201-Tl and 99m-Tc gated SPECT (QGS-A)methods. We studied 79 patients(48 men, 31 women; mean age 70±14 yr)with cardiomyopathy(n=4)and ischemic(n= 57)or congestive heart disease(n=18). Methods: All subjects were investigated as to the correlation between values with QGS-A and UCG. Either 201-Tl(n=51)or 99m-Tc(n=28)gated SPECT was performed at rest(n=48)or stress(n=3l)stage followed by UCG within one month. Gated SPECT data, including EDV, ESV, and LVEF, were quantified by using an automatic algorithm as QGS-A, whereas UCG data(EDV, ESV, and LVEF)were determined by the standard technique. Results: A significant correlation was found between 201-Tl or 99m-Tc QGS-A and UCG with respect to EDV, ESV, and LVEF(201-Tl: r=0.761, 0.882, 0.819; 99m-Tc: r=0.515, 0765, 0695, respectively, all p values < 0.01), regardless of the use of rest images. The mean values of EDV, ESV, and LVEF calculated by QGS-A were significantly lower than those of UCG(all p values <0.01). Conclusion: LV volumes and LVEF calculated by both 201-Tl and 99m-Tc QGS-A were significantly correlated with those obtained by UCG. These findings support the clinical significance and validity of 201-Tl and 99m-Tc QGS-A for simultaneously assessing both LV function and myocardial perfusion imaging.
公益社団法人日本放射線技術学会の論文
2001-11-20