hollow fiber dialyzerを用いたGd-DTPAのボーラス注入におけるT_2^*変化の解析

概要

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It has been demonstrated in a simulation that diffusion is an important component in determining T_2^* contrast. When a high-susceptibility agent permeates from intravascular to extracellular space, the changes in its spatial distribution affect the signal intensity of T_2^*-weighted images so as to potentially represent a diffusion process. To experimentally demonstrate the effects of permeation on T_2^*-weighted images, we assessed the dynamic changes in T_2^* signal after a bolus injection of Gd-DTPA(Magnevist:Schering)solution into a hollow fiber dialyzer as a phantom of intravascular and extracellular space. The signal intensity of the hollow fiber dialyzer in gradient-echo images was compared with that in spin-echo images.
社団法人日本放射線技術学会の論文
2000-08-20