Intermediary Metabolism in Castrated/Thyroidectomized Calotes versicolor : Regulation by Thyroxine and Testosterone(Endocrinology)

概要

論文の詳細を見る
Thyroidectomy did not change blood glucose level and acid phosphatase (Ac. Pase; liver and kidney) activity, and castration reduced the same in Calotes versicolor, when compared to their respective sham-operated controls. Castration or thyroidectomy decreased the activities of glucose-6-phosphatase (G-6-Pase; liver and kidney), glutamic oxaloacetic transaminase (GOT; liver and heart), glutamic pyruvic transaminase (GPT; liver) and urea (liver and kidney) concentration. Thyroidectomy markedly elevated hepatic cholesterol level and castration did not change its concentration. Administration of thyroxine (T4) to castrated and testosterone (T) to thyroidectomized animals stimulated the activities of G-6-Pase, Ac. Pase, GOT, GPT, the concentrations of glucose and urea, and decreased liver cholesterol concentration. It is suggested that both T_4 and T are effective in stimulating intermediary metabolism in lizards, irrespective of the removal of either thyroid or gonad.
社団法人日本動物学会の論文
1992-10-15