C-reactive Protein (CRP) in Animals : Its Chemical Properties and Biological Functions

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概要

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• C-reactive protein (CRP), which was found in the sera of pneumococci in 1930 and has been used as a marker protein for inflammation in clinical laboratories, has been isolated as well from the sera of fishes and body fluids of invertebrates. Taking it into consideration that the evolutionary origin of this protein may be early enough, the CRP is supposed to act an important role. Recent studies on CRP have revealed the biological functions of this protein. For example, CRP and macrophages make up an amplification mechanism in primary stage of immune response. On the other hand, it was revealed that the serum level of CRP was controlled by not only interleukin(s) but also sex hormone(s).

• 1992-06-15

著者

• Nunomura Wataru

  Nippon Bio-test Laboratories. Inc. And Tumour Laboratory

関連論文

• C-reactive Protein (CRP) in Animals : Its Chemical Properties and Biological Functions

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