Rat Ghrelin Stimulates Growth Hormone and Prolactin Release in the Tilapia, Oreochromis mossambicus(Endocrinology)
スポンサーリンク
概要
- 論文の詳細を見る
Recently, ghrelin (Ghr), a new peptide which specifically stimulates growth hormone (GH) release from the pituitary, was identified in the rat and human stomach. Ghrelin has been shown to stimulate GH release by acting through a growth hormone secretagogue (GHS) receptor in the rat. The present study describes the in vitro effect of rat Ghr on the release of GH and two forms of prolactin (PRL_<177> and PRL_<188>) in the tilapia, Oreochromis mossambicus. Rat Ghr stimulated the release of GH in a dose-related manner after 8 and 24 hr of incubation. Rat Ghr also significantly stimulated the release of PRL_<177> and PRL_<188> in a dose-related manner after 24 hr. Rat Ghr had no effect on the pituitary content of GH or PRL_<188>, but significantly increased PRL_<177> content. These results show for the first time that rat Ghr significantly stimulates GH and PRL release in teleosts, and suggest that Ghr and a GHS receptor are present in fish.
- 社団法人日本動物学会の論文
- 2002-07-25
著者
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HIRANO Tetsuya
Hawaii Institute of Marine Biology
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Grau E
Hawaii Inst. Marine Biology Hawaii Usa
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RILEY Larry
Hawaii Institute of Marine Biology, University of Hawaii
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GRAU E.
Hawaii Institute of Marine Biology, University of Hawaii
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Grau E.
Hawaii Institute Of Marine Biology
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Riley Larry
Hawaii Institute Of Marine Biology University Of Hawaii
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Hirano T
Hawaii Institute Of Marine Biology University Of Hawaii
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