Expression Patterns of Smad Family Members during Embryogenesis of the Ascidian Halocynthia roretzi
スポンサーリンク
概要
- 論文の詳細を見る
The ascidian embryo has been long thought to show a mosaic mode of development. However, recent studies revealed significance of cell-cell communication during cleavage stages of embryogenesis. FGF and BMP signalings play critical roles in determination of cell types. Little is, however, known about regulation of competence of cells to the signals. Here we report the isolation of ascidian smad genes; Hrsmad4 which encodes a homolog of smad4 of vertebrates, Hrsmad6/7 which encodes a homologous gene of smad 6 and smad7 of vertebrates, and Hrsmad2/3 which encodes a homolog of smad2 and smad3 of vertebrates. The mRNAs of the isolated smad family genes were maternally inherited in egg and early embryos. While Hrsmad4 and Hrsmad6/7 RNAs distributed broadly in the early embryos, Hrsmad2/3 RNA was preferentially accumulated in the animal hemisphere.
- 社団法人日本動物学会の論文
- 2001-08-10
著者
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Makabe Kazuhiro
Department Of Zoology Graduate School Of Science Kyoto University
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Kobayashi Ako
Department Of Zoology Graduate School Of Science Kyoto University
関連論文
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- The ascidian embryo: An experimental system for studying genetic circuitry for embryonic cell specification and morphogenesis
- Neural Marker Genes Differently Expressed in Subsets of Embryonic Neural Cells of the Ascidian Halocynthia roretzi
- A Large-Scale Whole-Mount in situ Hybridization System: Rapid One-Tube Preparation of DIG-Labeled RNA Probes and High Throughput Hybridization using 96-Well Silent Screen Plates
- A maternal RNA encoding smad1/5 is segregated to animal blastomeres during ascidian development
- Failure of Muscle Myosin Heavy-Chain Gene Expression in Quarter Ascidian Embryos Developed from the Secondary Muscle Lineage Cells(Developmental Biology)
- Expression Patterns of Smad Family Members during Embryogenesis of the Ascidian Halocynthia roretzi
- Ascidian Wnt-5 gene is involved in the morphogenetic movement of notochord cells