Hormonal Regulation of Biosynthesis of Major Plasma Proteins in Bombyx mori(Biochemistry)

概要

論文の詳細を見る
A group of structurally related proteins, termed "30K Proteins", accumulates in the hemolymph of the last instar larvae of the silkworm, Bombyx mori. Hormonal regulation of biosynthesis of these plasma proteins was studied by means of allatectomy and in vitro culture of fat body. When corpora allata were exterpated from the day-1-old fourth instar larvae, 30K protein components appeared in the hemolymph 2 days after operation. The rate of the 30K protein synthesis in the fat body of the allatectomized larvae reached maximum 3 days after operation then declined. On the other hand, the fat body from the sham-operated larvae synthesized only a trace of 30K proteins throughout the fourth larval instar. Larvae that had been allatectomized at the end of the fourth instar period normally molted. The induction of the 30K protein synthesis was also observed in the fat body of the allatectomized last instar larvae 2 days after feeding. From these results it is suggested that the biosynthesis of 30K proteins in the fat body is selectively induced by the disappearance of juvenile hormone from hemolymph under high nutritional condition.
社団法人日本動物学会の論文