Ionic Dependence of the Axotomy-Induced Long-Lasting Firing in an Identified Crayfish Motoneuron

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概要

• 論文の詳細を見る

• I have reported previously that axotomy of an identifiable anal motoneuron of crayfish Procambarus clarkii induces a long-lasting firing and that a prolonged depolarizing pulse to its cut end can induce a similar response. In this study, I confirmed that this stimulus is comparable to axotomy ; the frequency of stimulus-induced firing increases linearly with the stimulus intensity and its firing pattern is the same as that following axotomy. Then, when the cut end was bathed for more than 1 hr in test solutions, it was examined whether the stimulus to the cut end induces or blocks the response. Na^+-free saline(Tris^+ replaced Na^+)or TTX (3×10^<-7>M)reversibly blocked the response within 30 min. By contrast, Mn^<2+> saline(40 mM Mn^<2+> replaced Ca^<2+>)or Ca^<2+>-free salines(Mg^<2+> or 1 mM EDTA replaced Ca^<2+>) cannot block the response, but instead increased the firing frequency. These results obtained with stimulus were confirmed also by those with axotomy. I concluded that axotomy-induced firing, which occurs locally at its cut region, is primarily responsible for voltage-dependent Na^+ conductances, but not for Ca^<2+> ones.

• 社団法人日本動物学会の論文

著者

• MURAMOTO Atsuko

  Fukushima Biomedical Institute of Environmental & Neoplastic Disease;

• Muramoto Atsuko

  Fukushima Biomedical Institute Of Environmental And Neoplastic Diseases

関連論文

• -288-BASIC STUDIES ON THE MEASUREMENT OF MICROMAGNETIC SIGNALS OF HUMAN SUBJECTS AND THE MAGNETOCARDIOGRAM : Arrythmia, His Bundle Electrogram, Electrophysiology : PROCEEDINGS OF THE 42nd ANNUAL MEETING OF THE JAPANESE CIRCULATION SOCIETY
• Axotomy-induced Long-lasting Firing in an Identified Crayfish Motoneuron
• Spontaneous Firing in the Isolated Anucleate Axonal Segment of an Identified Crayfish Motoneuron(Physiology)
• Ionic Dependence of the Axotomy-Induced Long-Lasting Firing in an Identified Crayfish Motoneuron

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