Proliferation of Anterior Pituitary Cells in Relation to Aging and Longevity in the Rat

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概要

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• Some of the hormones secreted from the anterior pituitary are related to the potency of survival during the aging process. The proliferation of thyrotrophs affects the lifespan of the rat through the activity of the thyroid gland. Adrenocorticotropic hormone promotes the deterioration of brain function in aged rats. Average prolactin levels and the incidence of prolactinoma increase in aged rats. A longitudinal study showed that the increase in prolactin levels represents the precancerous state for a prolactinoma. Culture experiments indicate that the proliferation of acidophils is regulated by hypothalamic growth hormone-releasing factor and other hormones, which are possibly responsible for the age-related change in acidophil populations.

• 社団法人日本動物学会の論文
• 1993-06-15

著者

• Ooka Hiroshi

  Department Of Cell Biology Tokyo Metropolitan Institute Of Gerontology

関連論文

• Proliferation of Anterior Pituitary Cells in Relation to Aging and Longevity in the Rat

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