Cytochalasin B Affects Selectively the Marginal Cells of the Epithelial Sheet in Culture : Cell Biology and Biochemistry
スポンサーリンク
概要
- 論文の詳細を見る
The epithelial spreading is a fundamental one among morphogenetic movements. To know the mechanism generating force for spreading, the effect of cyiochalasin B (cytB) on the corneal epithelium in culture was investigated. Fourμg/ml of cytB inhibited completely the epithelial spreading and, at the same time, altered selectively the shapes of marginal cells: they shrinked at leading lamella and retracted quickly leaving fine tails behind, in which the bundles of F-actin were disintegrated to be numbers of fragments, while most of the other cells kept their shapes unchanged, along the cell borders of which F-actin distributed as before the treatment of cytB . The high sensitivity of the marginal cells to cytB led us to consider that F-actin was incessantly polymerized and taken into the intracellular organs generating force which enabled the marginal cells to locomote outwards, and that the outward locomotion, as a main force, spread entire epithelium.
- 社団法人日本動物学会の論文
- 1987-06-15
著者
-
Takeuchi S
Dep. Of Biology Fac. Of Sci. Okayama Univ.
-
TAKEUCHI SHIGEO
Zoological Institute, Faculty of Science, University of Tokyo
関連論文
- TRANSFORMING GROWTH FACTOR α EXPRESSION IN THE MOUSE UTERINE ENDOMETRIUM
- EFFECT OF STEROID HORMONES, GROWTH FACTORS AND CYTOKINES ON THE EXPRESSION OF MATRIX METALLOPROTEINASE mRNAS IN THE MOUSE UTERUS
- SEX STEROID HORMONES REGULATE TRANSFORMING GROWTH FACTOR-α mRNA LEVELS IN MOUSE UTERINE CELLS
- THE ROLE OF INTERLEUKIN-18 FOR APOPTOSIS IN THE MOUSE TESTIS
- WIDESPREAD EXPRESSION OF SENSE AND ANTISENSE TRANSCRIPTS OF THE GROWTH HORMONE GENE IN THE CHICKEN
- EFFECT OF ESTRADIOL-17β ON GENE EXPRESSION OF INTERLEUKIN-18 IN MOUSE REPRODUCTIVE ORGANS
- REGULATION OF PROOPIOMELANOCORTIN GENE EXPRESSION IN CORTICOTROPIC TUMOR AtT-20 CELLS
- EPIDERMAL GROWTH FACTOR AND ITS RECEPTORS IN THE MOUSE PITUITARY GLANDS
- ACTIVATION OF RECEPTORS FOR EPIDERMAL GROWTH FACTOR(EGF) IS REQUIRED FOR ESTROGEN-INDUCED PROLIFERATION OF MOUSE PITUITARY CELLS
- STRUCTURE AND EXPRESSION OF THE CHICKEN PRO - OPIOMELANOCORTIN (POMC) GENE
- Cytochalasin B Affects Selectively the Marginal Cells of the Epithelial Sheet in Culture : Cell Biology and Biochemistry