The Mediation of Cyclic AMP in Octopaminergic Modulation at Neuromuscular Junctions of the Mealworm, Tenebrio molitor : Physiology

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概要

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• The possibility that there is mediation of cyclic AMP in the octopaminergic modulation of neuromuscular transmission was examined. Octopamine (1μM) potentiated the amplitude of neurally-evoked excitatory junctional potentials (EJPs) at the neuromuscular junctions on the ventral longitudinal muscle of the mealworm, Tenebrio molitor. Although lower doses of octopamine (0.01μM) or cyclic AMP (100μM) had no effects on EJPs, the amplitude of EJPs was potentiated by these compounds when the phosphodiesterase activity was inhibited with simultaneous application of phosphodiesterase inhibitor, isobutyl-1-methylxanthine (IBMX, 10μM). No effects of octopamine, cyclic AMP or IBMX on the time constant of the decay phase of the EJPs and the resting membrane potentials were observed. The results support the presynaptic mediation of cyclic AMP in octopaminergic modulation at neuromuscular junctions.

• 社団法人日本動物学会の論文
• 1987-06-15

著者

• Fukami Jun-ichi

  Institute Of Agriculture And Forestry University Of Tsukuba:laboratory Of Insect Toxicology Institut

• HIDOH OSAMU

  Institute of Agriculture and Forestry, University of Tsukuba

• Hidoh Osamu

  Institute Of Agriculture And Forestry University Of Tsukuba

関連論文

• The Mediation of Cyclic AMP in Octopaminergic Modulation at Neuromuscular Junctions of the Mealworm, Tenebrio molitor : Physiology

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