CHANGES IN ALKALINE PHOSPHATASE AND γ-GLUTAMYL TRANSPEPTIDASE DURING THE PROCESS OF RAT HEPATOCYTE PROLIFERATION
スポンサーリンク
概要
- 論文の詳細を見る
D-galactosamine was injected i.p. into rats at a single dose level of 250 mg/kg. Basophilic hepatocytes and their mitotic forms were observed 48 hr and 72 hr after the administration of the amino sugar. At these stages, the biochemical activities of alkaline phosphatase (ALPase) and γ-glutamyl transpeptidase (γ-GTP) in rat liver homogenate increased significantly in comparison to those in the control rats. In the histochemical analysis, 48 hr and 72 hr after administration of the amino sugar, a high level of activity of both ALPase and γ-GTP was seen along the cell borders between adjacent hepatocytes and along the entire hepatocyte surface. At the level of electron microscopy, the reaction products showing ALPase activity were observed in abundance along the complex interdigitation of the plasmamembranes, which were present on the cell borders between adjacent hepatocytes.
- 1989-00-00
著者
-
CHIDA KOHSUKE
Department of Pathology, Kitasato University School of Hygienic Sciences
-
Chida Kohsuke
Department of Anatomy, Kitasato University, School of Allied Health Sciences
関連論文
- Localization of Alkaline Phosphatase and Cathepsin D during Cell Restoration after Colchicine Treatment in Primary Cultures of Fetal Rat Hepatocytes
- Change in Localization of Alkaline Phosphatase and Mannosidase II by Colchicine Treatment of Primary Cultures of Fetal Rat Hepatocytes
- Effects of Colchicine on Localization of Alkaline Phosphatase in McA-RH 7777 Rat Hepatoma Cells
- Localization of Gamma-Glutamyltranspeptidase and Alkaline Phosphatase in Rat Hepatoma Cell Line, McA-RH 7777
- CHANGES IN ALKALINE PHOSPHATASE AND γ-GLUTAMYL TRANSPEPTIDASE DURING THE PROCESS OF RAT HEPATOCYTE PROLIFERATION
- Changes in Expression of Connexin 32, Bile Canaliculus-Like Structures, and Localization of Alkaline Phosphatase in Primary Cultures of Fetal Rat Hepatocytes
- The activity and histochemistry of enzymes during the proliferation process of rat liver cells
- IB-12 Correlation between the formation of bile canaliculi and localization of alkaline phosphatase(THE 46TH ANNUAL MEETING OF THE JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY)
- P-18 Localization of Alkaline Phosphatase and Gamma-glutamyltranspeptidase in Primary Cultures of Fetal Rat Hepatocytes
- Immunohistochemical Detection of Glutathione S-transferase P in Postnatal Rat Liver after Administration of Dexamethasone
- Localization of Gamma-glutamyltranspeptidase and Alkaline Phosphatase in Rat Cultured Hepatoma Cells
- Effect of Colchicine on Intracellular Transport of Alkaline Phosphatase in Primary Culture of Adult Rat Hepatocytes : Immunocytochemical Study