NEUTRAL ATP-HYDROLYZING ENZYME ACTIVITY ON THE PLASMA MEMBRANE OF OSTEOBLASTS
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概要
- 論文の詳細を見る
The ATP-splitting enzyme activity at the neutral pH range was localized on the plasma membrane of osteoblasts as well as in lysosomes of all kinds of bone cells. The ATP-splitting enzyme activity on the plasma membrane seems to be different from the lysosomal one. The enzyme is (a) resistant to EDTA-decalcification, (b) localized on the plasma membrane of metaphyseal osteoblasts, (c) dependent on Mg^<++> ion, (d) active in the neutral (pH 7.0-7.4) and moderately alkaline (pH 8.5) ranges, (e) inhibited by Ca^<++> ion or EDTA, but (f) not inhibited by ouabain, levamisole, L-cysteine, or NaF. From these findings, it can be concluded that the enzyme activity contains a moderate amount of adenylate cyclase.
- 日本組織細胞化学会の論文
著者
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Fukushima Osamu
Department Of Anatomy Jikei University School Of Medicine
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Goshi Norihisa
Department Of Anatomy Jikei University School Of Medicine
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Fukushima Osamu
Department Of Anatomy (i) The Jikei University School Of Medicine
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