Alkaline-phosphatase and Ca^<2+>-ATPase Cytochemistry of 'Seamless' Endothelial Cells in the Rat Brain
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概要
- 論文の詳細を見る
Capillaries having lumen formed by perforation of a single endothelial cell - the socalled seamless endothelial cell - have been reported by Wolff [30]. Seamless endothelial cells occur in the central nervous system and in other organs. This type ofcell is more frequently observed where there is extensive vascularization. In the rat, the blood-brain barrier (BBB) is completed around the third week after birth. The activities of several enzymes correlate well with the functional heterogeneity of themicrovascular endothelial lining. Alkaline phosphatase (ALPase) and Ca^<2+>- activated adenosine triphosphatase (Ca<2+>-ATPase) are representative enzymes revealing capillary permeability. In the present communication, the fine structural localizations of ALPase and Ca<2+>-ATPase were studied in the brain of young adult rats, with special attention being directed towards the enzymatic activities of seamless endothelial cells.
- 日本組織細胞化学会の論文
著者
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Fujimoto Katsukuni
Department of Urology, Kawasaki Medical School
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Fujimoto Katsukuni
Department Of Anatomy Kawasaki Medical School
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- Alkaline-phosphatase and Ca^-ATPase Cytochemistry of 'Seamless' Endothelial Cells in the Rat Brain