腎障害を有する患者に対する急性血液浄化法の成績(<特集>多臓器不全とアフェレシス)

概要

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Acute renal failure is induced easily in patients with mild renal dysfunction, and provides many unfavorable effects on patients with multiple organ failure. Six hundred thirty-six of 801 patients who received continuous renal replacement therapy (CRRT) in Saitama Medical School Hospital from 1998 to 2002 were retrospectively analyzed. The patients were divided into 4 groups according to their serum creatinine level at 2 weeks before receiving CRRT; Group1: serum creatinine level below 1.2 mg/dl, Group 2: serum creatinine level 1.2-3.0 mg/dl, Group 3: serum creatinine level over 3.0 mg/dl, and Group 4: patients receiving dialysis therapy. The survival rates at 30 days after the initiation of CRRT, were 52% in all subjects, 49% in the patients with diabetes mellitus, and 56% in the patients without diabetes mellitus. In Groups 3 and 4, the survival rates were significantly lower than for the patients in Groups 1 and 2. The patients over 75 years old showed a significantly lower survival rate than other age groups. From these results, the level of renal function and an age over 75 years old may become predictive factors in CRRT.
日本アフェレシス学会の論文
2004-02-29