劇症肝炎の内科的治療(<特集>劇症肝炎の治療をめぐって)

概要

論文の詳細を見る
The principles of medical therapy for fulminant hepatitis are correction and preservation of the metabolic environment perturbed by hepatic failure using plasma exchange combined with hemodialysis-filtration, reduction of hepatic inflammation, and management of complications such as brain edema, infection, gastrointestinal bleeding, renal failure and disseminated intravascular coagulation. These therapies should be carried out in parallel with strict monitoring and management of respiratory and circulatory systems in order to maintain the patient in good condition until the liver has regenerated sufficiently or liver transplantation is possible. Although the number of survival cases by living-related liver transplantation has increased in recent years, especially in patients with subacute cases, the shortage of donors in Japan keeps most patients in medical therapy. There is an urgent need to develop a therapy promoting liver regeneration for saving subacute-type patients.
日本アフェレシス学会の論文
2003-10-31