腎不全に併発する高血圧症についての研究 : 腎不全における血漿ReninおよびAngiotensinase活性についての検討

概要

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Plasma renin activity (PRA) and plasma angiotensinase (ATase) activity were measured in 3 patients with acute renal failure, 36 patients with chronic renal failure, 75 control patients with various types of hypertension or urological diseases, and 12 normal control subjects as well as in 18 dogs which were performed bilateral ureteral ligation, bilateral nephrectomy and control operation. The results were as follows: 1) PRA was increased significantly in the bilateral urcteral ligation group and was undetectable in the bilateral nephrectomy group of dogs. Plasma ATase activity in these two groups showed no significant difference from that in control group. 2) PRA was increased remarkably in 9 cases of renovascular hypertension and pyelonephritis in man. Other control groups rarely showed increased PRA. All of control groups were without marked by increased plasma ATase activity.
社団法人日本泌尿器科学会の論文