小児膀胱括約筋硬化症の研究

概要

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Histological examinations were given on the sepecimens of horizontal and vertical sections of the bladder necks and posterior urethras prepared from 7 autopsied cases of congenital idiopathic bladder neck obstruction (their ages ranging from 1 day to 4 years and 3 months) and from 10 normal cases (their ages being almost similar), with a view to elucidating the entity of this disease. 1) The vesical sphincter in normal cases was distinctly separated from the muscle layers, when seen on the horizontal specimens, and their muscle fibers were fine and even and that they were in close contact with connective tissues but were lacking in elastic fibers. The sphincter was observed to terminate in the vermontanum. 2) The vesical sphincter of congenital idiopathic bladder neck obstruction was observed to have intense fibrosis in 6 cases and fibroelastosis in 1 case. These changes were seen to have reached the vermontanum, decreasing in intensity gradually. Judging from those findings the entity of congenital idiopathic bladder neck obstruction can be concluded to have originated from congenital fibrosis in the vesical sphincter, and this disease is better called "congenital vesical sphincter sclerosis".
社団法人日本泌尿器科学会の論文