Povidone-Iodine(Isodine)の緑膿菌に対する殺菌効果と褪色について

概要

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Bactericidal activity of iodic antiseptic, Isodine, was studied by a method similar to that of the Phenol Coefficient. In the early stage of the experiments, bactericidal activity was found to be very labile. After many experiments however, it was found that the dark violet color of Isodine was faded by the peptone in the Trypticase-soy-broth and its bactericidal activity was reduced. To avoid the effect of peptone the saline was used to emulsify the colonies on G A M-agar-plate. 1,000 times diluted Isodine killed P. aeruginosa (8 strains), E. coli (NIHJ JC-2) and S. aureus (FDA209-P) within one minute. But 5,000 times diluted Isodine could not kill those bacteria within 15 minutes. No difference of bactericidal activity was observed between 20゜C and 37゜incubation.
社団法人日本泌尿器科学会の論文