造血器悪性腫瘍例における人精巣の変化 : 特に白血病例について

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The human testes in cases with malignant hematopoietic tumors, especially with leukemia, were histopathologically examined. Materials were obtained from 56 autopsy cases, composed of 47 with leukemia, 7 with reticulum cell sarcoma and 2 with lymphosarcoma. The results obtained were as follows: 1.Leukemic infiltration was confirmed in 43(91%) of all leukemia cases. The patterns of infiltration in the testes were divided into three types; diffuse, patchy and perivascular, according to the distribution of leukemic cells. A high grade infiltration was most commonly encountered in lymphatic leukemia and observed in 3 cases (44%), while in 4 cases (10%) in others. The leukemic infiltration preferred the interstitial space without involvement of seminiferous tubules. The testicular involvement was unexceptionally bilateral with occasional differences in the grade of infiltration, slight to moderate. 2.There was no regional difference in incidence of the leukemic infiltration in the testicular interstitial tissue. However, nodular foci of leukemic cell infiltration, 500u to 1OOOu in diameter, around the middle-sized blood vessels, were observed in 1O cases but the evidence of mural penetration was not confirmed.
社団法人日本泌尿器科学会の論文