ラット前立腺前葉の微細構造に関する研究特に下垂体摘除のおよぼす影響について : 第II報下垂体摘除ラット前立腺前葉の微細構造

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Changes in the glandular cells of the ventral lobe of the prostate in hypophysectomized rats were observed by electron microscopy, in order to investigate the influence of hypophysectomy on the prostate. 1) The earliest change in the fine structure was derangement and decrease of the rough-surfaced endoplasmic reticulum, which was even in the next day of the intervention. Three days later, the fattened cisternae were remarkably distended in irregular or circular forms. About a week after the intervention, the endoplasmic reticulum showed a marked decrease in the amount. Two months later, it was observed that only some vesicular remnants of the endoplasmic reticulum were dispersed through the cytoplasm. 2) On the fourth day, a remarkable diminution of secretory granules and apocrine-like cytoplasmic protrusions in their number was observed, which completely disappeared from the micrographs on the fourteenth day or later. 3) There appeared large cytolysomes in the cytoplasm after four days or later. They were surrounded by limiting membrane and contained a variety of membranous structures, such as vesicles, vacuoles. granules, and lamellar bodies, which were thought to be degenerated mitochondrias. Cytochemical method for acid phosphatase revealed some activities in the cytolysomes, indicating a disorder in the cellular metabolism. 4) On the other hand, a characteristic structure which might be similar to corpora amylacea in the human prostate appeared in the acinar lumen. A dense homogeneous material was placed in the central portion of it and showed a finer granular structure in the high magnified micrographs. In the peripheral zone of the structure there were stacked numerous vesicles and granules with various electron densities. The finding suggested a derangement in secretory activities.
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ラット前立腺前葉の微細構造に関する研究特に下垂体摘除のおよぼす影響について : 第II報下垂体摘除ラット前立腺前葉の微細構造

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ラット前立腺前葉の微細構造に関する研究特に下垂体摘除のおよぼす影響について : 第II報 下垂体摘除ラット前立腺前葉の微細構造

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ラット前立腺前葉の微細構造に関する研究特に下垂体摘除のおよぼす影響について : 第II報下垂体摘除ラット前立腺前葉の微細構造