尿路感染症におけるBacteria L-formの意義 : 特に腎盂腎炎発生機序に関する問題について : 第2報Bacteria L-formに実験的腎盂腎炎に関する研究

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Studies on experimental pyelonephritis by bacterial L-form : 1. In Wistar strain rats, pyelonephritis (or pyelitis) could be experimentally produced by injecting E. coli K 12 penicillin induced L-form or E. coli K 12 lysozyme induced L-form into either vein or renal medulla. 2. In the group of intravenous injection L-form could be detected in 2.38% from renal tissues and in 0.48% from urine, whereas in the group of direct injection into the renal medulla renal tissue specimen showed L-form in 26.19% and urine specimen in 1.00%. 3. It has been proved that bacterial L-form is alive within the mucous membrane of the pelvis, under the mucous membrane of the pelvis or in submucous adipose tissue of the pelvis. 4. There was no correlation between normal intestinal bacteria and inoculated E. coli K 12 L-form in wistar strain rats. 5. Electron microscopic examination has disclosed that there are many round or ellipsoid large bodies with various sizes, which are surrounded by a monolayer of the unit membrane and have filament-like structure, in the mesenchyma of the pelvis and that the large bodies resembling the above ones are also present in the cells of arterioles or veins in part.
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