神経因性膀胱に関する実験的研究 : 第17報 : 成犬における下部腰髄の膀胱支配に関する新知見

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概要

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• It is generally accepted that the urinary bladder of the dog is innervated by two nerves; namely, the hypogastric nerve originating from L_1-L_3, which is sympathetic, and the pelvic nerve originating from S_1-S_3, parasympathetic. Since the nature of the "Basal Rhythm of the Bladder (BR)" has been examined corresponding to the various selective sections of related nerves, the author has had to assume that the lower lumbar segment of the spinal cord would have some important role on the functional control of the urinary bladder. Therefore, to clarify the mode of the innervation, patho-physiological alteration of the vesical function and retrograde urethral resistance 3 weeks after selective section of the lower lumbar spinal nerves (L_5-L_7) was examined, as well as the vesical response against selective electrical stimulation on an adequate area in the lumbar spinal cord, and also on the histological aspect of the vesical wall after the nerve section. The results obtained were as follows: 1)The spinal reflex contraction of the bladder observed on the cystometrogram was disappeared after bilateral resection of the ventral root and the spinal ganglion, section of the ventral root, resection of the spinal ganglion, proximal section of the dorsal root or the ventral-and-dorsal roots, of the L_5-L_7 lumbar nerves, as well as bilateral section of the ventral rami of the same lumbar nerves. But it was retained after bilateral interganglionic (L_<3-4>) section of the sympathetic chains, or resection of the L_7 and S_1 sympathetic ganglions.

• 社団法人日本泌尿器科学会の論文

著者

• 今林 健一

  東北大学医学部泌尿器科学教室

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• 神経因性膀胱に関する実験的研究 : 第17報 : 成犬における下部腰髄の膀胱支配に関する新知見

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