犬膀胱筋電図に関する実験的研究

概要

論文の詳細を見る
Electrical activity of urinary bladder was studied in 34 female mongrel dogs. Bipolar electrodes (Fig. 1) were fixed on the serosal surface of the bladder to record electrical activity. Intravesical pressure was simultaneously recorded. Results obtained were summarized as follows. 1) When the bladder was empty and quiescent, electricai activity of detrusor muscle was also in practically resting state (Fig. 2). 2) As intravesical fluid volume and intravesical pressure increased, spike potentials started to occur and its frequency increased with increasing in pressure. 3) Existence of prevoiding pressure as reported by Gierup et al. was confirmed immediately before micturition reflex (Fig. 5). Electrical activity of detrusor muscle increased at this time. 4) Electrical activity of the detrusor showed maximum when micturition reflex occurred. The spike potentials had a duration of 0.1 to 0.2 sec. and an amplitude of 10 to 50μV, and appeared at a frequency of 2 to 6/sec. . 5) Upon intermittent quick infusion of 10 ml. saline into the bladder, while intravesical fluid volume was still small, there was only a transient rise in intravesical pressure and no change in electrical activity. As intravesical fluid volume increased and detrusor muscle was stretched to a certain degree, intravesical pressure showed a step-wise increase at each infusion and electrical activity became intensive enough to bring about a voiding reflex. This would suggest that, when initially relaxed detrusor muscle was gradually stretched and its tonus finally passed a threshold, the resulting contractile force due to the stretch reflex became great enough to squeeze out the stored fluid.
社団法人日本泌尿器科学会の論文

犬膀胱筋電図に関する実験的研究

スポンサーリンク

概要

著者

関連論文

スポンサーリンク