特発性精索静脈瘤 : 第1報睾丸機能について

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Seventeen cases of varicocele with disturbance of spermatogenesis were studied for volume of bilateral testes, sperm count, histology of bilateral testes, plasma testosterone on HCG (10,000 i.u./M^2 i.m.), and plasma LH and FSH on LH-RH (100μg/M^2 i.m.). Volume of left testis in all cases and right testis in nine cases were lower than that of normal Japanese males. Spermatograms were oligospermia (n=6) and azoospermia (n=11). Histology of bilateral in all cases were from 5 to 9 on Johnsen's score count. In comparison of score count between left and right, left disturbances were more remarkable in seven cases, but inverted pictures were existed in two cases. There was a significant linear correlation between volume of left testis and score count of left testis (r=0.70, p<0.01). Plasma testosterone and response on HCG were not lower in statistics between normal adult males, but increases on HCG were smaller in cases with low score count than cases with high score count. Plasma LH and FSH, both basal and on LH-RH were not higher in statistics than normal adult males. FSH seemed significant inversed linear correlation with score count from left testis (r=-0.57, p<0.02).
社団法人日本泌尿器科学会の論文