冷凍外科のラット舌におよぼす影響に関する実験的研究
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概要
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A pathohistological study was made with use of 63 Wistar-strain rats on the behaviour of tongue tissue after cryosurgery. The freezing temperatures chosen were -50℃, -100℃ and -160℃ for 60 seconds. The results were as follows : 1. Epithelial tissue degenerated and disappeared to the 5th day after freezing, and the beginning of regeneration was on the 7th day after freezing. To the 22nd day, conjunction of epithelial tissue was restored. 2. To the 3rd day after freezing, breakdown and disapperance of the muscular bundles developed in the muscular tissue at the center of the frozen area. Arrangement and runing of muscular bundles were recovered on the 22nd day. 3. To the 5th day after freezing, blood vessels fell into breakdown and disappearance, and thrombus covered a wide area extending to the zone of muscular tissue. On the other hand, small blood vessels began to regenerate about the same time. 4. In the groups of below -100℃, thrombus was found in larger vessels and in wider areas than in the group of -50℃. 5. When larger vessels were frozen, these vessels fell into thrombus ; therefore, secondary injury of distal tissues was found. 6. Nerve tissues in the area of freezing fell into degeneration. Degeneration became severer to the 3rd day after freezing. Regeneration of nerve fibers began from the 5th day. Restoration of nerve distribution was on the 14th day in the group of -50℃, and on the 22nd day in the other groups. 7. Degeneration of nerve fibers extended to the larger nerve bundles in the medial and deep regions of the tongue. And this appearance was more remarkable and extended to the distal region in the groups below -100℃ than in the group of -50℃. 8. Regeneration of nerve fibers and recovery of nerve distribution were delayed in the groups of lower temperatures under -100℃ 9. Under the freezing temperature of -50℃, tongue tissues fell into degeneration, breakdown and disapperance at the center of the frozen area. These findings were found in wider areas in the groups of lower temperatures. 10. The tongue healed with a scar centering around the frozen area and with more remarkable deformation of the tongue in the groups under -100°.
- 九州歯科学会の論文
- 1988-06-25