成長期の虚弱骨下顎頭に対する食餌療法に関する実験的研究 : 骨基質形成
スポンサーリンク
概要
- 論文の詳細を見る
Diet therapy for debilitated bone of low aged children in particular among those in childhood is considered to greatly affect bone tissue at the growing stage. For this study, 3-week-old male Wistar rats corresponding to the weaning stage of human beings were used and diet therapy for debilitated mandibular condyle was carried out, and formation of bone matrix was investigated especially. The results were as follows : 1. Radiological and bone density findings : In diet therapy for debilitated mandibular condyle in the experimental group, as compared with the control group, bone construction in compactness and bone density of chondroitic layer and osseous layer excelled in the order of the control group, normal diet group, and high calcium diet group. Between the normal diet group and high calcium diet group, no significant differences were found. 2. Analytical findings on the X-ray microanalyzer : In quantitative analysis of Ca and P, relative Ca was higher in the control group, followed by normal diet group and high calcium diet group in the descending order. Relative P was in the descending order of the normal diet group, control group, and high calcium diet group. 3. Histopathological findings : Although the normal diet group and high calcium diet group, as compared with the control group, showed no changes in chondrocytes in the static zone, the chondroitic layer was wider, but chondroitic ossification and bone quantity were reduced greatly. Furthermore, the normal diet group and high calcium diet group, as compared with the control group, showed decrease in bone construction of chondroitic layer and trabeculae. 4. Scanning electron microscopic findings : In the normal diet group and high calcium diet group, as compared with the control group, chondroitic lacunae and bone lacunae on the surface of bone matrix fromation were incomplete. The high calcium diet group especially as compared with the normal diet group showed abundant distribution of collagen fibrills on the surface of bone matrix formation. On the basis of the foregoing findings the diet therapy for debilitated mandibular condyle was carried out, the normal diet group and high calcium diet group as compared with the control group showed decrease in the formation of bone matrix. Furthermore, the high calcium diet group as compared with the control group, showed decrease in the formation of bone matrix due to reduction in mineral content when excessive administration of calcium was maintained for an extended period.
- 九州歯科学会の論文
- 1995-08-25
著者
関連論文
- 成長期顎骨の実験的骨粗鬆症に対する高カルシウム食の影響に関する研究 : とくに歯槽骨の変化
- 成長期の虚弱骨下顎頭に対する食餌療法に関する実験的研究 : 骨基質形成 : 主論文の要旨
- 成長期の虚弱骨下顎頭に対する食餌療法に関する実験的研究 : 骨基質形成