ウサギ口蓋扁桃における食菌細胞の動態に関する実験的研究
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概要
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The purpose of this paper is to show the phagocytotic response to penetrated microorganism in tonsil of rabbits. After application of living or dead Candida albicans by dripping near by the organ in the throat of rabbits, the numbers of phagocytes which engulfed the yeast and not engulfed ones were counted in several areas of palatine tonsil. The proportions of phagocytosis were calculated from the number. Localization of immunoglobulin positive cells was also studied in the tonsil. Results are as follows : 1. After application of dead yeast, the proportions of the phagocytosis were 33-54% in crypt epithelium and basal membrane, 40-58% in germinal center and interfollicular area, and 60-68% in a part of capsula nearby efferent lymphoduct. 2. After application of living yeast, the proportions of the phagocytosis were 23-42% in crypt epithelium and basal membrane, 45-55% in a part of capsula nearby efferent lymph-oduct, and 63-68% in germinal center and interfollicular area. 3. After application of dead yeast with lipopolysaccharide, the proportions of the phagocytosis were 35-56% in crypt epithelium and basal membrane, 30-49% in germinal center and interfollicular area, and 23-28% in a part of capsula nearby efferent lymphoduct. 4. After application of living yeast with lipopolysaccharide, the proportions of the phagocytosis were 50-67% in crypt epithelium, 37-42% in a part of capsula nearby efferent lymphoduct, and 26-33% in germinal center and interfollicular area. 5. In the study of immunoglobulin, the immunoglobulin positive cells were detected in the area between basal membrane and crypt epithelium including a part of lymphoepitherial symbiosis. Above results showed that the active part of phagocytosis in tonsil was affected by the viability of microorganisms. Lipopolysaccharide which was applied with microorganisms, affected the time of phagocytosis in tonsil. These results showed that the phagocytosis in tonsil was affected by the composition and nature of antigens.
- 九州歯科学会の論文
- 1993-02-25