唾液の流出障害をおこさせたイヌ顎下腺の変化に関する組織化学的研究

概要

論文の詳細を見る
After excretory disturbance of saliva induced by injection of silicone impression material into the excretory duct of the submaxillary glands of dogs, the macroscopic, histopathological and histochemical investigations were undertaken from the first to 26th postoperative weeks. The following results were obtained. 1. The macroscopic findings In the early stage after operation, the submaxillary glands changed edematous with faintly red color, hereafter, it varied from white to dark brown, reduced in diameter and hardened. In the soft x-ray's findings, the radiopaque picture was shown reaching to the acinar hilus of the excretory ducts, which were expanded with time. 2. The histopathological findings After the operation, atrophy and disapperance of the acini, the dilatations of intercalated ducts, strated ducts, interlobular ducts and the proliferation of inflammatory granulation tissue occurred, which were severely changed with time. In the 8th week after the operation, the lobular structure was destroyed. In the 26th week after the operation, the proliferation of inflammatory granulation tissue was prominent and the acini, intercalated ducts, striated ducts became indistinct, while the proliferation of epithelial cells occurred. 3. The histochemical findings 1) The intense alkaline phosphatase activity was seen in the myoepithelial-cells and capillaries in the control groups. After the operation, this intense activity was maintained, showing a little variation. The slight activity was observed in the striated ducts and interlobular ducts, which gradually decreased after operation. 2) The intense acid phosphatase activity was seen in the serous cells, striated ducts and interlobular ducts in the control groups. The extremely intense activity was shown in the degenerated, atrophied acini and the remaining cells between the acini. The activity in the striated ducts and interlobular ducts gradually decreased after operation. 3) The intense succinic dehydrogenase activity was seen in the serous cells, intercalated ducts, striated ducts and interlobular ducts in the control groups. However, this activity decreased with time after the operation. In the 26th week after the operation, the cells were observed, which displayed the intense activity in the areas which would appear to be the remnant of the intercalated ducts and striated ducts. 4) The intense lactate dehydrogenase was observed in the serous cells, intercalated ducts, striated ducts and interlobular ducts and this activity in each area decreased until the third postoperative week. In the 8th week after the operation, the relatively intense activity was displayed in the contents of the lumens and ducts. In the 26th week after the operation, the intense activity was seen in the areas, which would appear to be the remnant of the acini and intercalated ducts. The slight activity was also observed in the inflammatory granulation tissues.
九州歯科学会の論文
1986-10-25

唾液の流出障害をおこさせたイヌ顎下腺の変化に関する組織化学的研究

スポンサーリンク

概要

著者

関連論文

スポンサーリンク