永久歯歯胚を含む下顎骨有形片の近遠心転換移植に関する実験的研究
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As regards to the study on the transplantation of the tooth germ have been made and reported by Kostecka (1968), Lapchinsky & malinovsky (1941), Ijiri & Suganuma (1943), Shapiro & Maclean (1945), Masuda (1959), Kirino (1960), and others. However, study on the transplantation of the mandibular bone block with tooth germ, except for Ijiri & Yamakawa (1959), Toyoshima (1972), as far as the author has read, could hardly be found. Clinically, some cases of fracture of the jaw and face in young patient, we often meet with involved free bone fragment with permanent tooth germ. In such cases, when free bone fragment with tooth germ made combined transplantation, that was interested in odontologically how about healing process may be traced. The author proved to determine and recongnize the attitude of permanent tooth germ and the healing process of mandibular bone block that was immediately transplanted mandibular bone with changing mesial for distal after resection of complete separation of continuity in infant dogs. The study was made by macroscopical, roentgenological and patho-histological courses. The result on this article are summarized as follows. 1. From 3 to 5 days postoperatively, the reactive cells infiltration was appeared in basal part of the dental papilla, and disordered arrangement of the odontoblasts was observed. The blood clots filled the space between the transplanted mandibular bone and the recipient bone edges. 2. From 10 to 14 days postoperatively, the basal part of the dental papilla and dental sac of the tooth germs was melted and disappeared to become cavityzation. The blood clots showed the tendency of organization, and it replaced, more and more, by the fibrous connective tissue. The new bone began to develop along inferior border of the recipient bone. 3. From 21 to 45 days postoperatively, the tooth germ was melted, in the dental papilla, except enamel and dentin and immature bone appeared along surrounding bone tissue following dental sac had been almost disappeared. The new bone began to develop along the inferior border of the recipient bone remarkably, about 30 days postoperatively, new bone trabeculae was shown union with each other in a greater or less degree. 4. About 60 days postoperatively, the dental papilla and dental sac were filled with fibrous connective tissue, but enamel and dentin partially remaind, and there had been replaced by new bone. Also both transplanted bone and recipient bone was shown complete union with new bone, the part of it has been formatived lamellated bone. 5. The last day of experimental about 120 days, the tooth germ was completely disappeared, and transplanted bone was completely replaced by new bone. The new bone which was recipient bone and transplanted bone, was developed into the bone with neary normal structure histologically and roentgenological. Morphologically, experimental side nearly resembled structure comparing to control side except fourth premolar defected. The findings and facts described above, both transplanted bone and recipient bone was shown complete union with the formation of new bone, more and more, they was replaced by normal bone, finally it has been resembled to jaw bone of control side, morphologically and histologically. But to my regret the permanent tooth did not show eruption itself.
- 九州歯科学会の論文
- 1976-01-31
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