固有唾液の pH と意識レベルとの関係(観察編)
スポンサーリンク
概要
- 論文の詳細を見る
1) A role of the salivary glands playing in maintaining isohydric homeostasis of the blood or body fluid was investigated by comparing the pH of human proper saliva, consecutively measured with B.T.B. pH test papers, with the levels of consciousness which were subjectively sensible as clear or drowsy. This report may also somewhat contribute to clarify the presence or significance of an excretory function taking place through the salivary glands. 2) In addition to biorhythmical circadian fluctuation of salivary pH reported previously, the change in pH of proper saliva depending upon a dominancy of each of the autonomic nerves was evidently found out by detecting continuously both salivary pH and the state of consciousness. Experimentally, the pH was as low as 6.5 or less in the time of clear consciousness, whereas it was slightly high as 6.8 or more than this value in the light drowsy state. From the viewpoint of the autonomic nervous activities it was presumed that the parasympatheticotonic condition, even when occurred either suddenly or gradually, was favorable for an elevation in pH of excreted proper saliva to a value of about 6.8. 3) An increase in pH to about 6.8, taking place with gradual or sudden patterns, distinctly signified a loss of consciousness expressible psychophysiologically by light sleep. Even sudden return of the lost consciousness to a normal state did not cause parallel immediate recovery of the pH values to previous levels. In these observations, the limit of the pH values which distinguished clear consciousness from drowsy one was 6.8. The inertia of the change in salivary pH was found to be about ten minutes. 4) Supposedly, the fluctuation of salivary pH values is not only a sequence of hypothalamic autonomic capability but a peripheral one such as a change in absorption process in the salivary glands. A part of neural mechanisms determining conscious level will control a dominancy of each of both autonomic nervous systems. When parasympatheticotony is present, the salivary pH will refer to an active excretion or a passive leakage of HCO_3^- from the blood. In detail, the content of this anion in blood might be increased either by hypothalamic control for blood electrolyte distribution or by reabsorption increase in the kidney, resulting in salivary pH elevation by the salivary glands which are hypothetically excretory in nature partially. As a result of the deviation of autonomic isohydric activities, the salivary glands, probably behaving like leaky machinery for blood electrolytes, may cause an elevation of salivary pH via the change in HCO_3^-. 5) Autonomic activity, either sympathotonic or parasympathotonic dominancy, behaves as a modulator of the circadian pH rhythm which is an expression of salivary contribution to maintenance of body fluid pH. A role, not essential but less, of the salivary glands playing as a regulator for blood pH was supposed. The supposition described here will be confirmed by animal experiments in the near future.
- 九州歯科学会の論文
- 1973-11-30