Xanthomatous Lesion of the Gingive: A possible cause of delayed tooth eruption

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概要

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• The authors report the rare case of a granular cell lesion of the gingiva overlying a maxillary incisor tooth that was delayed in eruption in a 9-year-old Japanese boy. The lesion was composed of a nodular aggregation of ovoid-shaped cells with eosinophilic and granular cytoplasm, which was immunohistochemically positive for LDL, CD68, HLA-DR, cathepsin D and heparanase. These cells were neither positive for S-100 protein, vimentin, desmin nor myosin. The results suggested that this lesion is a sort of xanthoma, but neither granular cell tumor nor congenital epulis. The etiology of this lesion is unknown, but it seems to be associated with tissue remodeling processes of the pericoronal mesenchymal tissue during tooth eruption. Such an unusual pericoronal tissue containing a xanthomatous lesion may be one of the causes for delay in tooth eruption.

• 特定非営利活動法人日本臨床口腔病理学会の論文
• 1999-12-20

著者

• SAKU TAKASHI

  Department of Biotechnology, The University of Tokyo

• ONO Yukiko

  Department of Bioscience, Tokyo University of Agriculture

• Ida-yonemochi Hiroko

  Department Of Pathology Niigata University School Of Dentistry

• Ono Yukiko

  Department Of Oral And Maxillofacial Surgery Niigata University School Of Dentistry

• Saku Takashi

  Department Of Pathology Niigata University School Of Dentistry

• Saku Takashi

  Department Of Biotechnology The University Of Tokyo

• NODA Tadashi

  Departments of Pedodontics Niigata University School of Dentistry,Niigata

• Noda Tadashi

  Department Of Oral Biological Science And Division Of Pediatric Dentistry Department Of Oral Health

• Noda Tadashi

  Department Of Pedodontics Niigata University School Of Dentistry

• Saku Takashi

  Department of Pathology, Niigata University School of Dentistry

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