An Analysis of Combined Inductive-Conductive Matrix and Autologous Bone Graft in 61 Posterior Cervical Fusions

概要

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Bioengineered gels may act as "graft extenders" supplementing bone harvested from the posterior iliac crest during posterior spinal fusions. Inductive Conductive Matrix (ICM-Sofamor Danek, Medtronic, Memphis, TN), a demineralized bone matrix, was utilized to extend and supplement grafts in 61 posterior cervical fusions. Plated anterior cervical corpectomy with fusion (average 2.8 levels) accompanied by simultaneous posterior wiring and fusion was performed in 61 patients (C2-T1). Halo devices immobilized patients until fusion was documented. The average age was 52 years and each exhibited moderate/severe preoperative myelopathy and mild postoperative myelopathy. They were followed an average of 4.3 years. Postoperative 2D-CT studies and dynamic X-rays were obtained 3, 6, and up to 12 months postoperatively until fusion was complete. Posterior wiring and fusion (PWF) in all 61 patients was supplemented with posterior iliac crest autograft, ICM, and cancellous allograft bone chips. Patients fused an average of 4.8 months postoperatively which was documented on postoperative 2D-CT studies in all cases. Conclusions : Supplemental ICM and iliac crest autograft resulted in 100% posterior fusion rate confirmed on 2D-CT studies in 61 patients undergoing circumferential cervical surgery.
日本脊髄外科学会の論文
2003-03-31