ニコチン酸代謝に関にする研究 : (III)健康人の6-ピリトン尿中排泄量に関する研究補遺

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Following researches were made on serial and individual fluctuations of the nicotinic acid metabolism in healthy body by measuring the excretion of N'-methyl-3-carboxylamide-6-pyridone in urine. The data reported in the previous papers should be corrected as follows : 1) The average excretion of N'-methyl-3-carboxylamide-6-pyridone in urine per day (12 men and 6 women) was 11.8±2.30 mg. The individual and serial fluctuations were remarkable. 2) Proportion of excretion of the three products from nicotinic acid metabolism in urine was estimated as 100 : 192 : 492 for nicotinic acid : N'-methylnicotinamide : N'-methyl-3-carboxylamide-6-pyridone. 3) The average total excretion of nicotinic acid metabolism products in urine per day (12 men and 6 women) was 15.3±2.56mg.
日本ビタミン学会の論文