放射線照射のビタミンB_1代謝に及ぼす影響
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概要
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The effect of X-ray irradiation on thiamine metabolism and its mechanism were studied on albino rats and mice. The irradiation of 800 roentgens on the whole body of a white rat caused after 24 hours, a decrease of the thiamine content in each organ and increases in the blood and urine. For studying the mechanism, thiamine load experiments and in vitro experiments using mitochondria were made. An inhibition of thiamine phosphorylation was found. In preventing a mouse from the X-rays effect, thiamine propyldisulfide was fairly active, and α-lipoic acid and thiamine diphosphate slightly active.
- 日本ビタミン学会の論文